After getting back to winning ways in the Champions League against Villarreal on Wednesday, Manchester United are set to host Rafa Benitez's Everton on Saturday in the Premier League.

A late Cristiano Ronaldo goal against the LaLiga Santander side gave the Red Devils their first win in three games in all competitions to secure all three points at Old Trafford.

Marcus Rashford, Amad Diallo and Harry Maguire will all miss the Everton clash due to injury, while Luke Shaw is expected to return to action after missing out on the game against Villarreal with a knock.

Meanwhile, Everton will take to the Old Trafford pitch without various players, including key starters, as Andre Gomes, Dominic Calvert-Lewin, Fabian Delph, Seamus Coleman and Richarlison are all sidelined with injuries.

Both Jordan Pickford and Alex Iwobi have also picked up knocks, but they are expected to be at Benitez's disposal for the game against United.

The Toffees currently sit fifth in the Premier League table, but the Red Devils will the first 'Big 6' team they will have faced this season.

Manchester United vs Everton predicted line-ups

Manchester United's predicted line-up: David de Gea; Aaron Wan-Bissaka, Victor Lindelof, Raphael Varane, Luke Shaw; Nemanja Matic, Fred; Mason Greenwood, Bruno Fernandes, Paul Pogba; Cristiano Ronaldo.

Everton's predicted line-up: Jordan Pickford; Ben Godfrey, Yerry Mina, Michael Keane, Lucas Digne; Andros Townsend, Abdoulaye Doucoure, Allan, Alex Iwobi; Demarai Gray; Salomon Rondon.

Manchester United vs Everton: When does it start?

The Premier League match between Manchester United and Everton is scheduled to kick off on Saturday at 12:30 BST. For those living in the USA, you can tune in at 07:30 ET/04:30 PT.

Manchester United vs Everton: Where to watch it?

This Premier League Matchday 7 match between Manchester United and Everton will take place on Saturday, October 2, at Old Trafford.

For those living in the USA, you can watch the game live on NBC Sports App, UNIVERSO NOW, nbcsports.com, UNIVERSO, Telemundo Deportes En Vivo and NBCSN.

Meanwhile, for those living in the UK, the match will be broadcast on BT Sport 1 and will also be streamed via the BT Sport website.